I recently delivered my first printed circuit board layout project using libre software. It’s an actively regulated, high current power supply for an audio equipment manufacturer, and it should be on the shelves in a month or so. The software used was KiCad (GPL2), though I did use FreeRouting (gratisware) to help route the board. I am quite happy with the results and the process. The work was done completely in Linux (Debian Wheezy, if you’re curious), proving that libre EDA–including the OS–is entirely possible.
Except for autorouting, the overall experience was comparable to working with my previous go-to package: the now-defunct WinQCad. While FreeRouting’s autorouter seems comparable to the best that other high-value EDA tools can presently offer, WinQCad’s was in a class of its own. FreeRouting still gets the job done, but it needs more hand-holding and prodding.
In addition to using it for PC layout, I am also using KiCad as a front-end schematic capture tool for SPICE simulations. Now that I’m over the worst of the learning curve, I’m really looking forward to doing more work in KiCad.